The amino acids that are forbidden to represent classes: G P
Group 1: QE
Group 2: KINFMXTR
Group 3: LUSWC
Group 4: VAD
Group 5: HY
Group 6: G
Group 7: P
Chronology: MXQUVHFIKTWNAGEYDCPSRL
ch_p_sim: 17.6824
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H
Group 1: VDA
Group 2: WULS
Group 3: HQE
Group 4: TIKNFMXR
Group 5: YC
Group 6: G
Group 7: P
Chronology: MXVWQCIKFTUNAHYPDGESRL
ch_p_sim: 17.6577
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H W
Group 1: HQE
Group 2: FKMTXNIR
Group 3: YC
Group 4: SWUL
Group 5: VDA
Group 6: G
Group 7: P
Chronology: MXQYUVIKTFWNAHGPDCESRL
ch_p_sim: 17.6513
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H W Q
Group 1: MTKXNIRF
Group 2: ULWSC
Group 3: EQ
Group 4: VAD
Group 5: HY
Group 6: G
Group 7: P
Chronology: MXUEVYIKTFWNAHGQDCPSRL
ch_p_sim: 17.6436
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H W Q U
Group 1: MNKXIRTF
Group 2: YH
Group 3: VAD
Group 4: CLWSU
Group 5: EQ
Group 6: G
Group 7: P
Chronology: MXYVCEIKTFWNAHUQDGPSRL
ch_p_sim: 17.6386
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H W Q E
Group 1: TMKXINF
Group 2: R
Group 3: VDA
Group 4: HYQE
Group 5: UWSLC
Group 6: G
Group 7: P
Chronology: MXRVYUIKTFWNAHGDCPQESL
ch_p_sim: 17.5816
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H W Q Y
Group 1: EQ
Group 2: MXWYC
Group 3: HUSL
Group 4: VDA
Group 5: TKFIRN
Group 6: G
Group 7: P
Chronology: MXEUVFIKTWNHAGQYDCPRSL
ch_p_sim: 17.634
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H W Y
Group 1: KRIFTN
Group 2: MXCW
Group 3: VDA
Group 4: UYLS
Group 5: HQE
Group 6: G
Group 7: P
Chronology: MXFVUQIKTWNHAGYPDCERSL
ch_p_sim: 17.6445
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H W Y F
Group 1: ULSY
Group 2: MXCW
Group 3: ADV
Group 4: HQE
Group 5: IKFRTN
Group 6: G
Group 7: P
Chronology: MXUAQIKFTWNHVGYPDCERSL
ch_p_sim: 17.5551
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H W Y U
Group 1: CSUL
Group 2: TFIKNR
Group 3: MXYW
Group 4: VDA
Group 5: HQE
Group 6: G
Group 7: P
Chronology: MXCFVQIKTWNHAUPYDGESRL
ch_p_sim: 17.6411
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H W U
Group 1: FRTNKIMX
Group 2: CULS
Group 3: HEQ
Group 4: VAD
Group 5: YW
Group 6: G
Group 7: P
Chronology: MXCQVYIKTFHNAUWPDGESRL
ch_p_sim: 17.6418
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H W U C +
Group 1: FRKINTMX
Group 2: VDA
Group 3: HQE
Group 4: YWC
Group 5: USL
Group 6: G
Group 7: P
Chronology: MXVQYSIKTFHNAWUPDCEGRL
ch_p_sim: 17.6354
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H Q
Group 1: FNKTRIMX
Group 2: LSUC
Group 3: VAD
Group 4: EQ
Group 5: YHW
Group 6: G
Group 7: P
Chronology: MXUVEWIKFTHNACQDYGPSRL
ch_p_sim: 17.6538
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H Q E
Group 1: KFNITMX
Group 2: VDA
Group 3: SLYU
Group 4: QHWE
Group 5: RC
Group 6: G
Group 7: P
Chronology: MXVUWRIKFTHNAGYDCPQESL
ch_p_sim: 17.596
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H Q E U
Group 1: EQHW
Group 2: MKTXIFN
Group 3: VAD
Group 4: CULYS
Group 5: R
Group 6: G
Group 7: P
Chronology: MXWVCRIKFTHNAUYDGPQESL
ch_p_sim: 17.5895
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H Q E R
Group 1: DAV
Group 2: HULS
Group 3: MXY
Group 4: WQE
Group 5: IKRTCFN
Group 6: G
Group 7: P
Chronology: MXAUWIKFTQNHVGYPDCERSL
ch_p_sim: 17.519
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H C
Group 1: VDA
Group 2: SUCL
Group 3: HYW
Group 4: KMXNIFRT
Group 5: EQ
Group 6: G
Group 7: P
Chronology: MXVUWEIKFTHNACQDYGPSRL
ch_p_sim: 17.6538
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H C U +
Group 1: ADV
Group 2: XKMIFNTR
Group 3: YCW
Group 4: EHQ
Group 5: USL
Group 6: G
Group 7: P
Chronology: MXAWQSIKFTHNVYUPDCEGRL
ch_p_sim: 17.6384
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H C U Q
Group 1: ITRFKMXNC
Group 2: WYH
Group 3: VDA
Group 4: LSU
Group 5: EQ
Group 6: G
Group 7: P
Chronology: MXWVSEIKFTHNAUQDYPCGRL
ch_p_sim: 17.6345
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P H C U S
Group 1: USLW
Group 2: HQE
Group 3: VDA
Group 4: MXY
Group 5: TIRKFNC
Group 6: G
Group 7: P
Chronology: MXWQVIKUTFNHAGYPDCESRL
ch_p_sim: 17.5489
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P U
Group 1: EQ
Group 2: VDA
Group 3: SUCLW
Group 4: IRMXKNTF
Group 5: HY
Group 6: G
Group 7: P
Chronology: MXEVCHFIKTWNAUQYDGPSRL
ch_p_sim: 17.6764
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P U C
Group 1: MNFIXTRK
Group 2: QE
Group 3: WUSCL
Group 4: HY
Group 5: AVD
Group 6: G
Group 7: P
Chronology: MXQWHAIKUTFNVGEYDCPSRL
ch_p_sim: 17.6737
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P U C W
Group 1: AVD
Group 2: TFNIMXRK
Group 3: SUL
Group 4: EQW
Group 5: YCH
Group 6: G
Group 7: P
Chronology: MXASQHFIKTWNVUPYDCEGRL
ch_p_sim: 17.6547
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P U C W S
Group 1: KXMIRTNF
Group 2: UYSL
Group 3: HCW
Group 4: QE
Group 5: ADV
Group 6: G
Group 7: P
Chronology: MXYHQAIKTFUNVGWEDCPSRL
ch_p_sim: 17.6449
--------------------------------------------------------------------------
The amino acids that are forbidden to represent classes: G P U C W Q
Group 1: DVA
Group 2: SUL
Group 3: TNFMXKIRC
Group 4: EQ
Group 5: WYH
Group 6: G
Group 7: P
Chronology: MXVSEHFIKTWNAUQDYPCGRL
ch_p_sim: 17.6495
--------------------------------------------------------------------------
0 input database // 0=Leipzig, 1=UCSC, 2=Poznan, 3=testLeipzig, 4=testUCSC
D acidType // R means tRNAs, D means tRNA genes (=tDNAs)
1 ARCHAEA_ARE_INCLUDED // 1 = yes, 0 = no
1 BACTERIA_ARE_INCLUDED
1 EUKARYOTES_ARE_INCLUDED
0 VIRUSES_ARE_INCLUDED // only for tRNA genes of database 0
0 SPECIES_ARE_SELECTED
0 numOfSpecies
species
-----------------------------------------------------------
3 function // 0=FindLUCA,1=FindScores,2=FindNonStartAAs,3=FindNonGlobAAs,4=GlobOptimizeGroups,5=TestData
0 FIRST_AA_IS_TESTED // 1=all AAs are tested at the 1st position, 0=>see the next row
M firstAA // only when FIRST_AA_IS_TESTED = 0
-----------------------------------------------------------
0 modified_nucleotides // 1=are distinguished (only for tRNAs), 0=not, 2=combined
0 topology // 0 = periodic code
0 aaRS_class // 0 = amino acids of both classes are included, 1 = type I, 2 = type II
1 X_IS_INCLUDED // Ini, i.e., initiation signals
1 O_IS_INCLUDED // Sup, i.e., termination signals
1 U_IS_INCLUDED // Sec, i.e., selenocisteine
1 MX_MOVE_TOGETHER // 1=Met and fMet/Met-ini move together, 0=no
1 NONSTANDARD_ASSIGNMENTS // are 0=ignored or 1=processed according to amino acids
-----------------------------------------------------------
5 numOfOptimizableGroups
2 numOfOneElementGroups
G P oneElementGroups
1 groupWeight // vs. familyWeight=1
-----------------------------------------------------------
0 numOfNonStartAAs
nonStartAAs
-----------------------------------------------------------
1 GLOBAL_ADAPTATION
0 numOfNonGlobAAs
nonGlobAAs
3 globStart // numbering starts from 1
----------------------if-database=1------------------------
1 ISOTYPE_MUST_BE_BEST_MODEL
0 primary
----------------if-database=1-&-function!=1----------------
67 score cutoff min
150 score cutoff max
0 isoscore cutoff min
150 isoscore cutoff max
0 isoscore_ac cutoff min
150 isoscore_ac cutoff max
----------------if-database=1-&-function=1-----------------
0.5 scoreStep[0] // min score
65 scoreStart[0]
110 scoreStop[0]
1 scoreStep[1] // min isoscore
0 scoreStart[1]
0 scoreStop[1]
1 scoreStep[2] // min isoscore_ac
0 scoreStart[2]
0 scoreStop[2]
1 scoreStep[3] // max score
150 scoreStart[3]
150 scoreStop[3]
1 scoreStep[4] // max isoscore
150 scoreStart[4]
150 scoreStop[4]
1 scoreStep[5] // max isoscore_ac
150 scoreStart[5]
150 scoreStop[5]
-----------------------------------------------------------
2 NumOfMatingsAndMutations
16 numOfTrimmedClassifications 2 4 8 16 32 48 64
0 softwareBruteForce // 0 = basic level, 1,2 = more brute force
0 hardwareBruteForce // 0 = basic level, 1,2 = more brute force
-----------------------------------------------------------
0 ISOACCEPTORS //1=similarities among isoacceptor tRNAs/tDNAs are also computed, 0=no
0 isoWeight // vs. alloacceptorWeight=1 // only when ISOACCEPTORS = 1
16 min number of assignments
15 max number of non-starting AAs
1 SAVE_DATA // save x_tRNA.txt or x_tDNA.txt on a harddisk
0 PRINT_UNRECOMMENDED_DETAILS // if function < 4, the ouput files can get too long
-----------------if-DOMAINS_ARE_WEIGHTED=1-----------------
1 archaealWeight // default=1
1 bacterialWeight // default=1
1 eukaryoticWeight // default=1
0 virusesWeight // default=0, when some is not default or function=0, then DOMAINS_ARE_WEIGHTED=1
0 BACTERIAL_AND_EUKARYOTIC_WEIGHTS_STAY_EQUAL // only for function = 0
-----------------------if-function=0-----------------------
1 domainStep[0] // archaeal weight
1 domainStart[0]
3 domainStop[0]
1 domainStep[1] // bacterial weight
1 domainStart[1]
3 domainStop[1]
1 domainStep[2] // eukaryotic weight
1 domainStart[2]
3 domainStop[2]
1 domainStep[3] // viral weight
0 domainStart[3]
0 domainStop[3]
-----see-the-bottom-for-a-check-of-included-positions------
0 included_parts // 0=Giege,1=E.coli,2=S.cerevisiae,3=blocks,4=Lin,5=custom
3 IE cutoff min // only when included_parts < 3
=0(all), =1(identity elements (IEs)), =3(effective IEs), =5(major IEs), =10(most MIEs)
--------------------if-included_parts=3--------------------
1 IS_ACCEPTOR_STEM
3 IECutOffMin3[0]
1 IS_D-ARM
3 IECutOffMin3[1]
1 IS_ANTICODON_ARM
3 IECutOffMin3[2]
1 IS_VARIABLE_LOOP
3 IECutOffMin3[3]
1 IS_T-ARM
3 IECutOffMin3[4]
1 IS_8th_SITE
3 IECutOffMin3[5]
1 IS_9th_SITE
3 IECutOffMin3[6]
1 IS_26th_SITE
3 IECutOffMin3[7]
1 IS_73rd_SITE
3 IECutOffMin3[8]
1 IS_74th_SITE
3 IECutOffMin3[9]
1 IS_75th_SITE
3 IECutOffMin3[10]
1 IS_76th_SITE
3 IECutOffMin3[11]
1 IS_ANTICODON
1 IS_INTERSECTION_WITH_GIEGE
0 IS_INTERSECTION_WITH_E.COLI
0 IS_INTERSECTION_WITH_S.CEREVISIAE
--------------------if-included_parts=4--------------------
0 ARE_SITES_UBIQUITOUS
0 ARE_SITES_NEAR_UBIQUITOUS
1 ARE_SITES_ISOTYPE_DISCRIMINATORS
0 ARE_SITES_CLADE_ISOTYPE_DISCRIMINATORS
0 ARE_SITES_ISOTYPE_SPECIFIC
0 ARE_SITES_TERTIARY_INTERACTING
0 ARE_SITES_A_BOX
0 ARE_SITES_B_BOX
--------------------if-included_parts=5--------------------
11111111 Acceptor stem 5'->3' // 1 = included, 0 = excluded
11111111111 3'->5'
11111111111111111 D-arm 5'->3'
1111 3'->5'
1111111111111 Anticodon arm 5'->3'
111111 3'->5'
1111111111111 Variable loop 5'->3'
1111111111 3'->5'
111111111111 T-arm 5'->3'
11111 3'->5'
333 a check of consistency
---------------a-check-of-included-positions---------------
Included sites of tDNAs (written only after the start of the program):
Acceptor stem: 01111100 D-arm:00110101000001000
00011111100 1101
Anticodon arm:0000000011111 Variable loop:1111111111111 T-arm:000000000000
100000 1111111111 00000
-----------------------------------------------------------
THE SIMULATION HAS FINISHED.
-------------------------------------------------